SST Cautions

Before ordering SST, please read the following information:

Basic Recommendations:

We recommend that you always consult with your physician before undertaking any new health practice. If you have any questions or concerns regarding this product, we recommend speaking with your primary care provider.

Cautions and Contraindications

Existing Lung Impairment:

One key concern is a report of lung difficulties among some users. Out of the 1.5 million prescriptions written in Japan, it was found that 1 in 20,000 had contracted pneumonitis, or interstitial pneumonia, serious conditions of the lung that results in inflamed airways. So, just to be safe, patients with underlying lung issues are recommended to avoid this remedy.

Pneumonitis was most often found in elderly, frail or infirm patients. People who already had an underlying lung disease, or who continued taking the product after breathing difficulties began, experienced a poorer outcome with this condition.

This is the Japanese government’s actual recommended monitoring for physicians: exclude patients with lung disease, cigarette smokers and asthmatics. Screen for abnormal lung function at baseline and one month on treatment, and screen patients during treatment for signs or symptoms of pneumonitis.

Patients need to monitor lung function closely. Any shortness of breath, persistent cough or congestion should be cause for concern and would necessitate the immediate cessation of SST.

Concurrent Interferon Usage:

Interferon, itself, can cause pneumonitis. For this reason persons taking Interferon should not take SST concurrently, as it may compound their risk of contracting pneumonitis.

Additional Glycyrrhizin Intake:

Anyone with hypertension (high blood pressure) should be advised to avoid products with licorice extract that contains very high levels of glycyrrhizin.

Glycyrrhizin has been shown to significantly up-regulate blood pressure.

SST contains glycyrrhizin but not enough to cause concern on its own.

Studies show the potential side effect of hypertension by glycyrrhizin happens only when the daily dosage of it is over 100 mg. When taken as directed, the amount of glycyrrhizin in SST is between 24.7 to 46.0 mg per day, which is well below the caution level.

When taking SST, patients should avoid other licorice-containing products that might increase the dosage of glycyrrhizin into the caution range.

Serious Pre-existing Liver Damage Caution:

SST is not recommended for patients who are both diagnosed with cirrhosis and have a platelet count below 100,000. In these cases, careful consideration by, and close supervision of, a physician to proceed with SST is strongly advised.

If you are diagnosed with cirrhosis, you should consult with your health care provider to determine your platelet count prior to taking SST.

Pregnancy and Lactation:

SST is contraindicated for women who are pregnant or nursing.

Additional Cautions:

A small percentage of individuals are sensitive to Bupleurum, the primary herb in this formula. If the following conditions worsen while taking SST, discontinue its use:

  • Migraine
  • Very high blood pressure (systolic over 180 mmHg)
  • Epistaxis (nose bleeds)

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