Liver Cancer

How is Liver Cancer Diagnosed?

Individuals chronically infected with the hepatitis B and hepatitis C virus should be screened periodically for hepatocellular carcinoma, as well as those individuals with cirrhosis, since about 80 percent of people with hepatocellular carcinomas have cirrhosis.

A thorough examination by a physician along with the following tests will diagnose liver cancer.

  • AFP test. Measures the blood level of a substance produced by some tumors called alpha-fetoprotein. Not all malignant tumors make AFP, however, and certain conditions, including pregnancy, viral hepatitis and some types of cancer can increase AFP levels.  
  • Liver Panel (Hepatic Function Panel). A blood sample is drawn from a vein in the arm to determine overall liver function.
  • Ultrasound. Used in conjunction with the AFP test for those at high risk of developing liver cancer, this non-invasive, painless procedure uses sound waves to produce images of the liver to show the shape, texture and location of tumors and helps in distinguishing whether a mass is cancerous or benign.
  • CT scan (computerized tomography). A painless, non-invasive test that uses a series of X-rays to produce high resolution images of the liver.
  • MRI (magnetic resonance imaging). A non-invasive, painless test that uses a powerful magnetic field, radio frequency pulses and a computer to produce detailed images of the liver and bile ducts. MRI does not use x-rays.
  • Liver biopsy. A small piece of tissue is removed from the liver using a long thin needle and then studied under a microscope.

American Cancer Society “What are the Key Statistics About Liver Cancer?” http://www.cancer.org/Cancer/LiverCancer/DetailedGuide/liver-cancer-what-is-key-statistics/ Retrieved March 22, 2011

American Liver Foundation “What is Liver Cancer?” http://www.cancer.org/Cancer/LiverCancer/DetailedGuide/liver-cancer-what-is-liver-cancer/ Retrieved March 22, 2011

Hepatitis-Central.com "Liver Cancer/Hepatocellular Carcinoma" http://www.hepatitis-central.com/hcv/hcc/toc.html Retrieved March 22, 2011

Mayo Clinic “Liver Cancer” http://www.mayoclinic.com/health/liver-cancer/DS00399/ Retrieved March 22, 2011

National Cancer Institute “What You Need to Know About Liver Cancer” http://www.cancer.gov/cancertopics/wyntk/liver/page1/ Retrieved March 22, 2011

Palmer, M.D., Melissa. Dr. Melissa Palmer’s Guide to Hepatitis & Liver Disease. New York: Avery Trade, 2004

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