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Gilbert Syndrome

What is Gilbert Syndrome?

Gilbert (pronounced zheel-BAYR) syndrome is a common, inherited, benign liver disorder. Gilbert Syndrome is not a disease but a normal variant in which individuals have mildly elevated bilirubin concentrations in their blood due to the liver’s inability to properly process bilirubin.

Bilirubin, a yellowish pigment, is a substance produced by the breakdown of old red blood cells and hemoglobin, the protein in red blood cells that carries oxygen from the lungs to the rest of the body. Normally, bilirubin is removed from the body through the digestive system (stool) as part of the bile from the liver. The amount of bilirubin in a person’s blood is usually very low.

Gilbert Syndrome is also known as constitutional hepatic dysfunction, benign unconjugated bilirubinemia and familial nonhemolytic jaundice.

American Liver Foundation “Gilbert Syndrome” http://www.liverfoundation.org/abouttheliver/info/gilbertsyndrome/ Retrieved March 30, 2011

eMedicine.com “Gilbert Syndrome”http://emedicine.medscape.com/article/176822-overview Retrieved March 30, 2011

Mayo Clinic “Gilbert’s Syndrome” http://www.mayoclinic.com/health/gilberts-syndrome/DS00743 Retrieved March 30, 2011

U.S. National Library of Medicine NIH National Institutes of Health “Gilbert’s Disease” http://www.nlm.nih.gov/medlineplus/ency/article/000301.htm Retrieved March 30, 2011

Worman, M.D. Howard J. The Liver Disorders and Hepatitis Sourcebook. McGraw-Hill, 2006

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