Acute Liver Failure

What are the Complications of Acute Liver Failure?

Acute liver failure often causes complications, some of which are:

  • Kidney failure – often occurs following liver failure, especially as a result of acetaminophen poisoning which damages both the liver and the kidneys.
  • Bleeding disorders - due to the body's inability to clot blood properly.
  • Infections – respiratory and urinary tract infections are common as well as infections in the blood.
  • Cerebral edema (excessive fluid in the brain) – leading to irreversible brain damage and death.
  • Coma – Mental confusion, difficulty concentrating and disorientation (hepatic encephalopathy) can progress to coma if liver function does not return.

Mayo Clinic “Acute Liver Failure” http://www.mayoclinic.com/health/liver-failure/DS00961. Retrieved May 20, 2011

Medscape “Diagnosis and Management of Acute Liver Failure” http://www.medscape.com/viewarticle/720697_3. Retrieved May 20, 2011

Palmer, M.D., Melissa. Dr. Melissa Palmer’s Guide to Hepatitis & Liver Disease. New York: Avery Trade, 2004.

U.S. National Library of Medicine NIH National Institutes of Health “Acute liver failure caused by 'fat burners' and dietary supplements: a case report and literature review” http://www.ncbi.nlm.nih.gov/pubmed/21499580. Retrieved May 20, 2011

U.S. National Library of Medicine NIH National Institutes of Health “Influence of high body mass index on outcome in acute liver failure” http://www.ncbi.nlm.nih.gov/pubmed/16996806. Retrieved May 20, 2011

Worman, MD Howard J. The Liver Disorders and Hepatitis Sourcebook. McGraw-Hill, 2006

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