Ref14P13
Pharmacological Research, Vol. 25, No. 2, 1992
Effect
of the Flavanolignans of Silybum marianum L. on Lipid Peroxidation
in Rat Liver Microsomes and Freshly Isolated Hepatocytes
ENRICA
BOSISIO, CINZIA BENELLI AND ONDINA PIROLA
Institute
of Pharmacological Sciences, Faculty of Pharmacy, University
of Milan, Italy
See
National Library of Medicine Citation
This
study examines the effect of several flavonolignans (silicristin,
silidianin, silybin and isosilybin) present in silymarin,
the extract of Silybum marianum fruits, was tested on lipid
peroxidation in rat liver microsomes and freshly isolated
hepatocytes.
The
study shows the antioxidant activity of the constituents in
silymarin, with silybin proving to be the most valuable.
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